Team

I received my PhD in Informatics from the  University of Verona in Italy.

I’ve developed skills in bioinformatics algorithm programming, graph analysis and algorithm development, data analysis and statistical analysis. Furthermore I’ve worked with genomes, variant data and different kind of genetic data including development of a software for in-silico CRISPR/Cas assessment and determination.

Currently, I am working on genomics data that includes single cell genomics, machine learning models and long read sequencing data analysis.

I received my Ph.D. in Pathology and Physiopathology at China Medical University in June, 2019 and then started my postdoc in Biswajyoti Sahu’s lab. Currently, my project focuses on the cell-fate conversion by direct reprogramming to make pancreatic excocrine cells. The goal is to understand the changes in 3D-genome architecture during this reprogramming process and getting better insight into the lineage-specificity of human cancers.

In particular, I use defined transcription factors for converting one cell type to another by a method known as transdifferentiation. The goal is to understand the role of these defined factors in modulating chromatin structure and gene expression during this dynamic process of transdifferentiation.

I completed my Masters Degree in the Molecular Bioscience and Biochemistry program from the University of Oslo in Norway. My Masters thesis work involved isolation and activation of Chronic Lymphocytic Leukaemia (CLL) cells. I was studying the effect of pharmacological inhibitors and monoclonal antibodies on the survival and proliferation of CLL cells for possible therapeutic development. The work involved multicolour flow cytometry, RNA work and confocal microscopy.

Currently, I am learning mammalian cell culture and modern genome-wide methods to understand chromatin structure, function and its role in gene regulation in human enhanceropathies such as in endometriosis and exploring parallels with cancer in terms of cellular plasticity.

I received my master’s degree in Toxicology from Sun Yat-sen University, China. My master’s thesis focused on the regulation of cancer-related epigenetic modifications using CRISPR-dCas9. Currently, at NCMM, I am working on identification of regulation elements involved in the initiation of liver cancer using methods of next-Generation Sequencing and employing CRISPR/Cas9 tools.

I completed my Master’s degree in Clinical Medicine at Capital Medical University in China. My research focuses on the role of the tumor microenvironment in pancreatic ductal adenocarcinoma (PDAC), particularly cancer associated fibroblasts, to further explore the pathophysiological mechanisms and identify novel precision targets. Currently, I am learning and working on organoid co-culture techniques, combined with the latest multi-omics sequencing methods, to understand the mechanisms of carcinogenesis and metastasis.

My background includes research in immunotherapy against solid cancer, specifically CAR T cells against Osteosarcoma, and general histology. I hold a B.Sc and M.Sc in Molecular Biology and Biochemistry from the University of Oslo.

I am studying for my Masters Degree in the University of Oslo.

Currently, I am learning cell culture methods in the lab and routine molecular biology techniques.

I am from Heidelberg in Germany and currently doing my Masters thesis project from University of Oslo.

Currently, I am learning molecular cloning work, plasmid preparation and lentiviral production to express my transcription factors of interest in lentiviral expression vector. In my project, I will be working with human 3D organoid cultures to express my transcription factors of interest and then study their role in gene expression and chromatin state.